Lucy Maria Tappan married Henry Chandler Bowen in 1844 when she was nineteen years old. She was the daughter of Lewis and Susanna Tappan of Brooklyn, New York. Henry and Lucy established their household in Brooklyn Heights, where their first child was born in 1845. Lucy gave birth to nine more children, seven boys and three girls, over the next eighteen years. She died in 1863, just two weeks after the birth of their tenth child, of childbirth complications.